What If I Said, It Wasn’t Me!

angrybugs It is far from uncommon for aggressive, uncontrollable behaviour to be blamed on the excessive consumption of sugar.

Experiments have, however, shown numerous ways in which interference with metabolic energy systems can be responsible, and on this basis, sugar can be very therapeutic.

Stress – or anything that interferes with thyroid function – tends to cause digestive processes to slow down, leading to a greater degree of fermentation of fibers and starches as well as a rise in the release of bacterial endotoxin.

This then results in the secretion of serotonin – and numerous other stress related substances – eventually increasing the toxic load placed on the liver.

Too much stress on the liver interferes with its ability to carry out its detoxification functions – allowing greater amounts of serotonin and endotoxin into the main system – promoting estrogen production and circulation (as well as inflammatory conditions in general), further interfering with thyroid and energy metabolism.

Both serotonin and estrogen are known to promote each others actions and in excess, have been closely associated with aggressive and violent behaviour.

Grains, beans and other starches – as well as large amounts of under cooked vegetable matter – can be strong promoters of bacterial overgrowth and regular consumption has the potential to feed a vicious cycle of thyroid suppression, as well as the eventual release of a variety of behaviour modifying substances.

Conditions of stress – and insufficient sugar – promote the release of the polyunsaturated fats from storage as free fatty acids in the blood, and these have been shown to significantly interfere with digestion (and thyroid function), as well as directly promoting the release (and actions) of estrogen and serotonin.

Saturated fats can be protective against the negative effects of the polyunsaturated fats. Fat produced by the body from excess sugar is largely saturated in nature (aside from the small amount of anti-inflammatory omega-9 fats produced under certain conditions), helping to shift the balance away from the dangerous unsaturated fats already stored in the tissue.

When circumstances are stressful, the body goes through glycogen stores at a much faster rate, and this – apart from causing the release of fat into the blood as an alternative fuel source – quickly leads to a rise in cortisol, in an attempt to provide required sugar via the breakdown of muscle and other tissue.

Cortisol – the basic hormone of stress – has been linked to increased aggression and can be effectively suppressed with the consumption of sucrose or fructose, both of which help to effectively replenish glycogen stores – as well as directly fueling metabolic energy systems – simultaneously protecting against some of the damaging effects of other stress substances such as estrogen and serotonin.

Serotonin has been experimentally demonstrated in many ways to be part of a behavioural system for harm avoidance, and in this sense, anything that lowers serotonin (or estrogen, as lowering estrogen tends to also lower serotonin), is likely to make a person feel less anxious and threatened, and consequently less prone to aggression. Anti-serotonin substances have been effective in the reduction of aggressive behaviour.

A diet low in fermentable fibers and starches, with sufficient protein (and some saturated fats) from milk, cheese and gelatinous cuts of meat, and plenty of easily digestible sugars from sweet ripe juicy fruits, fruit juice, honey and white sugar, is one rational approach to improving thyroid function, suppressing the overgrowth of bacteria, and reducing anti social and aggressive behaviour.

Sometimes it can be fair to say that how a person behaves from moment to moment, isn’t always completely in their control. Have you ever considered going the other way and trying a little more sugar? Just make sure it really is sugar that you are increasing.

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Effect of serotonergic drugs on the aggressiveness induced by delta 9-tetrahydrocannabinol in rem-sleep-deprived rats.

Effects of Estrogen on Aggressive Behavior

Individual differences in estrogen receptor alpha in select brain nuclei are associated with individual differences in aggression.

Maternal aggression in mice: effects of treatments with PCPA, 5-HTP and 5-HT receptor antagonists.

Anxiety and aggression associated with the fermentation of carbohydrates in the hindgut of rats.

Whole blood serotonin relates to violence in an epidemiological study.

5-HT1A and 5-HT1B receptor agonists and aggression: a pharmacological challenge of the serotonin deficiency hypothesis.

Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala

Effects of gepirone, an aryl-piperazine anxiolytic drug, on aggressive behavior and brain monoaminergic neurotransmission.

Effects of sugar on aggressive and inattentive behavior in children with attention deficit disorder with hyperactivity and normal children.

Hormone cortisol linked to increased aggression in 10-year-old boys

Cortisol responses to emotional stress in men: Association with a functional polymorphism in the 5HTR2C Gene

Inhibition of aggression by progesterone and its metabolites in female Syrian hamsters

Precursors to suicidality and violence on antidepressants: systematic review of trials in adult healthy volunteers

Serotonin activates the hypothalamic-pituitary-adrenal axis via serotonin 2C receptor stimulation.

Socially responsive effects of brain oxidative metabolism on aggression

Sweetened Blood Cools Hot Tempers: Physiological Self-Control and Aggression

Low glucose relates to greater aggression in married couples

High maternal intake of polyunsaturated fatty acids during pregnancy in mice alters offsprings’ aggressive behavior, immobility in the swim test, locomotor activity and brain protein kinase C activity.

Serotonin Synthesis and Reuptake in Social Anxiety Disorder

Are there differences in serum cholesterol and cortisol concentrations between violent and non-violent schizophrenic male suicide attempters?

Cholesterol concentrations in violent and non-violent women suicide attempters.

Elevated Plasma Inflammatory Markers in Individuals With Intermittent Explosive Disorder and Correlation With Aggression in Humans

Mechanism Linking Aggression Stress through Inflammation to Cancer

Elevated Plasma Oxidative Stress Markers in Individuals With Intermittent Explosive Disorder and Correlation With Aggression in Humans.

Antidepressants increase the risk of suicide, violence and homicide at all ages


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