Coffee For MS – It’s Wonderful!
If you’ve ever wondered why roughly twice as many women than men are diagnosed with MS every year, looking at ways that sugary coffee shields from the development of this – and other related conditions – can be illuminating.
Multiple sclerosis (MS) is known to arise in part because of an inflammatory process – damaging and interfering with the proper myelination of nerve cells – however, there are a number of explanations as to why this might occur, and some of them are more logical than others.
Nothing is ever black and white, but one thing that does seem clear, is that promoters of inflammation – such as serotonin, nitric oxide, prolactin, cortisol and the polyunsaturated free fatty acids – tend to be high in cases of multiple sclerosis (MS).
“Serotonin-induced platelet aggregation was increased in 40% of the MS patients…6 were suffering from an acute exacerbation of the disease at the time of measurement…serotonin-induced platelet aggregation was increased in all 6 of these patients…”
Looking at the different ways that stress rises in the context of a high estrogen, hypothyroid state – closely associated with MS and prevalent in women – can be one way to inspire meaningful discussion, and help formulate of a coherent and rational treatment approach.
Unfortunately, popular medical theories continue to enforce the idea that a so called estrogen deficiency makes women susceptible to MS, pushing estrogen supplements as one form of treatment.
For a belief system like this to be maintained – in order to prop up profitable agendas – physiology has to be turned upside down. This reduces any likelihood that clarity of understanding will arise discrediting the official story.
The most common theories are influenced by scientific misrepresentations promoting estrogen (rather than progesterone) as the female/pregnancy hormone, and by confusion about estrogen’s actions in relation to ‘birth control’ and the development of breast and other cancers.
Tied in with all of this are heavily endorsed and erroneous ideas – regarding serotonin and nitric oxide as well as the polyunsaturated fats – which grow out of poor foundational information, and are necessary to prevent the whole belief structure from crumbling.
The reigning confusion optimizes sales of a large number of pharmaceuticals and other treatment products.
Some things which require cognitive dissonance to survive on the market – and likely have a causative role in neurodegeneration – include most of the ‘anti-depressants’, estrogen drugs in general, cholesterol lowering statins, polyunsaturated seed and fish oils, even drugs like Viagra and Cialis.
A well functioning thyroid metabolism is protective against increasing and excessive levels of estrogen, restraining the rise of inflammatory and potentially neurodegenerative substances of stress.
Improvements in metabolic performance assist in the production of numerous highly protective and genuinely anti-inflammatory hormones (such as pregnenolone and progesterone), known to protect against the onset and worsening of MS symptoms.
“Observations…obtained in experimental autoimmune encephalomyelitis (EAE) have revealed the promising neuroprotective effects exerted by progesterone (PROG)…results indicate that PROG is effective in reducing the severity of chronic EAE and, consequently, may have potential with respect to MS treatment.”
When energy metabolism is suppressed and stress is high, digestion tends to be less effective often leading to the development of bacterial issues. Bacterial toxins promote serotonin and estrogen which help to drive what can be a self-feeding disregulated state of worsening inflammation and stress.
“Besides inflammatory bowel diseases…inflammatory diseases with remote tissues affected seem to be modulated by the gut environment; for example, in rheumatoid arthritis and type 1 diabetes mellitus……findings are of direct relevance to multiple sclerosis…”
This can be where coffee – consumed with sufficient quantities of sugar – enters the story.
Many studies show the protective effects of coffee (and caffeine), and it isn’t mere coincidence that coffee’s effects – which encourage efficient metabolic function – can help reduce the risk of development of MS.
Apart from having progesterone-like actions (protecting against damaging effects of estrogen and serotonin), caffeine acts somewhat similarly to thyroid, and helps boost the availability of active thyroid hormone.
Improved thyroid metabolism translates into more effective digestive function, reducing the potential for bacterial levels to get out of hand and for toxins to build up.
Regular coffee consumption improves liver function, increasing detoxification potential, leading to lower levels of estrogen throughout the system.
“There is emerging evidence for a hepatoprotective effect of coffee in a wide range of liver conditions of different severity ranging from elevation of liver enzymes to fibrosis and hepatocellular carcinoma.”
Improved liver function means better conversion of inactive thyroid hormone (T4) into active thyroid hormone (T3) and this is a central issue causing sub optimal thyroid function in women, and a common problem with MS.
The polyunsaturated fats (PUFA) interfere with the effectiveness of the active thyroid hormone (T3) and when stress is increasing and metabolism is being suppressed, polyunsaturated fats are released out of storage as free fatty acids, in greater amounts.
PUFAs powerfully promote inflammation and oxidative stress, which have been shown to play an important part in the development of MS, as well as neurodegeneration in general.
The breakdown products of the polyunsaturated fats also interfere with cholesterol creation and metabolism, impeding progesterone production and pushing the system in the direction towards more estrogen and cortisol and numerous other stress substances which damage brain function.
“Cholesterol availability is a prerequisite for myelination…remyelination failure in MS reflects, at least partially, the inability to locally increase the cholesterol content in demyelinated lesions.”
Sugar promotes the production of cholesterol and its conversion into the protective steroids. Sugar stimulates thyroid metabolism and suppresses stress, slowing the release of the inflammation promoting polyunsaturated free fatty acids.
These are just some of the ways that sugar can be understood to be a very important ingredient in any rational anti-MS strategy.
Blood sugar disregulation has been associated with the progression of multiple sclerosis. Sugar restriction – by lowering thyroid metabolism and increasing cortisol, estrogen, serotonin and free fatty acid levels – causes insulin resistance and furthers the hypo-metabolic conditions relevant to the onset of both diabetes and MS.
“The severity of cerebral hypometabolism was also related to the number of relapses…results suggest that measurement of cerebral metabolism in MS has the potential to be an objective marker for monitoring disease activity and to provide prognostic information.”
Caffeine has anti-serotonin effects and can protect against the absorption of iron. Both of these in excess are involved in the progression of MS. Not only is coffee a genuinely pro-thyroid food, it appears to be a worthwhile addition to any attempt to protect against or treat symptoms of MS and other estrogen related issues.
At this point I’m unaware of studies (looking at coffee’s neuroprotective effects) which have considered how the simultaneous addition of sugar might increase the healing power of coffee in relation to compromised metabolic function.
Many of the benefits which come from caffeine consumption – leading to an overall improvement in thyroid energy metabolism – can increase the quantity of sugar used throughout the system.
In the high estrogen, hypothyroid environment of MS – where liver function is often compromised and cortisol levels chronically raised – the ability of the liver to store glycogen is likely impaired.
“Neurological impairment…was more pronounced in the BDI high (elevated depression scores) group…there is evidence, that a hyperactive HPA axis is…present in MS patients expressing…elevated depressive symptoms…”
If – under circumstances like this – coffee is consumed with insufficient sugar, it can cause an unintended increase in stress, possibly interfering with its protective effects.
By promoting improvements in the performance of thyroid energy systems, sugar helps to promote the production of anti-stress and anti-aging steroid hormones – pregnenolone, progesterone, testosterone and DHEA – reducing and protecting from symptoms of MS.
“…progesterone and its derivatives might play a role in the control of the synthesis of the two major proteins of the peripheral nervous system (PNS): the glycoprotein Po (Po) and peripheral myelin protein…”
Sugar is necessary for optimal metabolic performance, and the anti-estrogenic effects of caffeine or coffee – and the brain protective effects of progesterone – make the argument for estrogen supplementation in MS seem illogical and irresponsible.
Coffee is one of the most widespread products on the planet and maybe that’s why it hasn’t been banned yet. That being said, there’s enough contradictory information dampening excitement about the health benefits of well sugared coffee, possibly enough to avoid the necessity for such extreme measures.
“High coffee consumption is associated with reduced odds of MS. Caffeine has neuroprotective properties and seems to suppress the production of proinflammatory cytokines, which may be mechanisms that explain the observed association.”
The authorities will say the cause of MS is unknown, or perhaps the result of insufficient fish oil consumption. Regardless, a diet protecting against the inflammatory by-products of stress and sub-optimal metabolism – which avoids the polyunsaturated fats, and includes sweet coffee, enough protein from milk, cheese or gelatin, and plenty of sugar from sweet ripe fruits, fruit juice, honey and white sugar – can be extremely helpful.
Some other things which might help to protect against MS include thiamine, biotin, aspirin, Minocycline, niacinamide, activated charcoal, methylene blue, vitamin E, cyproheptadine and some other antihistamines, and red light.
The truth is that the answers can’t be found in just one study. None of the biological conditions and symptoms discussed are individually responsible for the onset of MS. In reality they all exist together in one physiology. It is science and medicine that has been fragmented into non-existent specialties, often artificially contradicting each other, preventing understanding and genuine empowerment.
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