Aspirin! Because You May Not Need To F%#k Cancer After All.

wedopainkilling There are lots of reasons to be angry about cancer, but when you find out just how effective aspirin is as both a preventative measure and treatment – even cure – you might move from anger and suffering, skipping past worry and sadness, straight on up to murderous intent.

“We find that ASA [aspirin] not only prevents breast tumor cell growth…and tumor growth…but also significantly reduces the self-renewal capacity and growth of breast tumor-initiating cells/breast cancer stem cells…and delays the formation of a palpable tumor.”

Of course aspirin isn’t only effective in relation to cancer, because that isn’t how biology works and – contrary to the modern medical myth – cancer is actually a biological issue.

“Post-diagnosis use of aspirin in patients with gastrointestinal tract malignancies is associated with increased survival in cancers with different sites of origin and biology.”

In fact aspirin can be helpful with almost any physiological problem arising out of exposure – both internally and externally – to chronic and acute metabolic stress.

“…findings suggest that aspirin use may prevent incident breast, colon, pancreatic, and ovarian cancer in elderly women.”

“…aspirin…appears to reduce staphylococcal virulence…aspirin may have the potential to be an effective adjunctive agent in the treatment of serious hospital- or community-acquired S. aureus infections.”

“Aspirin can reduce oxidative stress and protect against oxidative damage….evidence suggests…beneficial effects of aspirin…in mood disorders and schizophrenia, and…data suggests…aspirin is associated with a reduced risk of AD [Alzheimer’s].”

Because aspirin helps to improve the function of metabolism in general. One way it does this is by protecting against the escalation of inflammation as well as a variety of other symptoms arising as a result of interference with thyroid energy systems.

“Epidemiologic and clinical studies indicate that inflammation is correlated with an increased risk of recurrence in breast cancer patients…multiple meta-analyses showed that patients with cardiovascular diseases treated with…aspirin, have reduced cancer risk.”

That’s basically why aspirin is beneficial in relation to protection from heart disease and stroke, but also for depression, diabetes and insulin resistance. And then there’s its use for the treatment of Alzheimer’s or for neuroprotection in general. Not to mention it’s effectiveness in relation to hypertension, pregnancy and fertility issues and an almost endless list of other symptoms or conditions.

“…neurological disorders, including Alzheimer’s…Huntington’s…and Parkinson’s disease…are characterized by accumulation of insoluble protein aggregates…aspirin inhibits protein aggregation…This mechanism may contribute to the neuro-protective, cardio-protective, and life-prolonging effects of aspirin.”

There is a huge amount of quality scientific experimentation (available for pretty much anybody to look at), which demonstrates the many powerful ways aspirin can protect against disease – including many regarding cancer – and not just simply as a preventative measure.

“We conducted a prospective study from 1992 through 1999 among 28 283 postmenopausal women…There was a trend of decreasing risk of pancreatic cancer incidence with increasing frequency of aspirin use per week.”

“…patients in the study had all stages of cancer at diagnosis—“When you look at the effects of aspirin stratified by cancer stage, you still see the same positive effects.””

And strangely enough, scientists (working for pharmaceutical companies) all over the world are using the physiological effects of aspirin as a model in their attempts to find a cure for cancer. Of course, that’s not really what they are looking for.

“…a novel, gastrointestinal-safe phosphatidylcholine (PC)-associated aspirin, PL2200 Aspirin, possesses the same or more pronounced actions versus unmodified aspirin with regard to antiplatelet effects…and chemoprevention.”

In reality what they want is to develop a product modeled on aspirin – providing similar positive results in relation to cancer – but different enough so that they can patent it and make oodles and oodles of dinero.

“…we report a significant reduction in HNC [head and neck cancer] risk with aspirin use, with the strongest protective effect for laryngeal cancers. No association was observed between HNC and ibuprofen use.”

Unfortunately however, there is no guarantee that whatever is produced will match the manner in which aspirin – tested for decades – works to safely provide physiological protection, including chemotherapy.

Many of the substances which rise in times of stress – serotonin, estrogen, histamine, the polyunsaturated free fatty acids and prostaglandins – do so as a result of the suppression of metabolic function.

“…results suggest that postmenopausal women who regularly use aspirin…may have lower estrogen levels…We observed significant inverse associations between total NSAID use and concentrations of estradiol and free estradiol…”

“Dietary soy isoflavones increase metastasis to lungs in a model of breast cancer and a recent study reported significantly increased cell proliferation in breast cancer patients who used soy supplementation. The soy isoflavone daidzein is a major food-derived phytoestrogen that is structurally similar to estrogen.”

A lack of energy supply – in combination with continuous exposure to excessive levels of these powerful promoters of inflammation – has been demonstrated to be a significant driving force behind the onset and development of cancer.

“…analgesics that decrease aromatase activity via suppression of COX expression and prostaglandin synthesis also may decrease estrogen concentrations and potentially risk of breast or ovarian cancer.”

Even when energy is being provided – and unused supplies are available – these (and numerous other) stress substances can be an important factor interfering with proper utilization, and this can make a return to normal function more difficult.

“…salicylate pretreatment prevents lipid-induced skeletal muscle insulin resistance…these results provide important new insights into the mechanism of fat-induced insulin resistance…and suggest a potentially novel class of therapeutic agents for type 2 diabetes.”

Aspirin helps to protect against stress and disease by improving the function of mitochondrial energy systems in a variety of ways which all seem to assist with the body’s natural biological processes, limiting interference with – and damage to – cellular performance from excessive exposure to cancer promoting substances such as estrogen and the polyunsaturated fats.

“Since FAs [fatty acids] are essential for cancer cell proliferation, limiting their availability could provide a therapeutic strategy. From the perspective of lipid metabolism, limiting FA availability could be achieved in several ways…”

“Abnormal lipid metabolism is a hallmark of tumorigenesis. Hence, the alterations of metabolism enhance the development of hepatocellular carcinoma (HCC)…Therapeutically, aspirin is potentially available for HCC through controlling abnormal lipid metabolism.”

You can see why aspirin is so frightening. For starters, if enough people were convinced of its protective ability in relation to cancer, that could go a long way towards destroying – or at least damaging – the extremely popular myth which states that ‘modern science’ is always moving forward towards greater understanding of the causes and treatments of serious illness.

“Aspirin inhibited glioma cell proliferation and invasive ability, and induced apoptotic cell death…results suggest that aspirin is a potent antitumor agent…”

“…salicylate…exhibit anti-tumor activity against…leukemia…We…tested…other NSAIDs, including acetaminophen and indomethacin…but did not detect any inhibitory activity…salicylate may be useful for treating inflammation, diabetes, neurodegenerative disease, and other pathologies…”

“Postmenopausal women who used ASA had a significantly lower risk of melanoma, and longer duration of ASA use was associated with greater protection.”

Furthermore, by shining a light of clarity and rationality onto some of the biologically more genuine explanations for the development of cancer, this could potentially cause a flow on effect, helping to unmask many other harmful products and treatment methodologies being sold on the basis of physiologically unsound justifications.

“Arachidonic acid (ARA) is metabolized by cyclooxygenase (COX) and cytochrome P450 to produce proangiogenic metabolites. Specifically, epoxyeicosatrienoic acids (EETs) produced from the P450 pathway are angiogenic, inducing cancer tumor growth.”

In some ways it can help to look at cancer – rather than simply as a disease – as something that can happen to your cells whilst they are doing the best they can do to keep you alive under the unnatural or exceedingly stressful conditions which they are being subjected to.

At moments like this it can almost seem a little more appropriate – rather than saying ‘f%#k cancer’ – to say f&$k the cancer industry, and all of the related industries which have been part of the process of muddying the waters surrounding the true causes of – as well as the really effective approaches to protecting against and treating – cancer, all in the name of power and greed.

“The present meta-analysis, which involves approximately 300,000 participants from 16 studies, has confirmed the antineoplastic effects of NSAIDs in multi-cancer metastasis…aspirin was the most predominant NSAID given to patients.”

You see, if everything can cause cancer, and nothing can really cure cancer, then it becomes easier to sell things which do cause cancer as well as other things which can’t really cure cancer, whilst at the same time avoiding competition from the sale of things that don’t cause cancer and other things which actually really do cure cancer. Was that clear?

See More Here

Aspirin blocks growth of breast tumor cells and tumor-initiating cells and induces reprogramming factors of mesenchymal to epithelial transition.

Aspirin Suppresses the Acquisition of Chemoresistance in Breast Cancer by Disrupting an NFκB–IL6 Signaling Axis Responsible for the Generation of Cancer Stem Cells

Aspirin use and the incidence of breast, colon, ovarian, and pancreatic cancers in elderly women in the Iowa Women’s Health Study

Association between nonsteroidal anti-inflammatory drug use and the incidence of pancreatic cancer.

Association of aspirin and nonaspirin nonsteroidal anti-inflammatory drugs with cancer incidence and mortality.

Effect of aspirin and other NSAIDs on postmenopausal breast cancer incidence by hormone receptor status: results from a prospective cohort study.

Association of aspirin and nonsteroidal anti-inflammatory drug use with breast cancer.

Nonsteroidal anti-inflammatory drugs and risk for ovarian and endometrial cancers in the Iowa Women’s Health Study.

Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials.

Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trials.

Aspirin and cancer risk: a quantitative review to 2011.

Aspirin, nonaspirin nonsteroidal anti-inflammatory drug, and acetaminophen use and risk of invasive epithelial ovarian cancer: a pooled analysis in the Ovarian Cancer Association Consortium.

Nonsteroidal anti-inflammatory drugs and risk of ovarian cancer: systematic review and meta-analysis of observational studies.

Aspirin might reduce the incidence of pancreatic cancer: A meta-analysis of observational studies.

Personalizing Aspirin Use for Targeted Breast Cancer Chemoprevention in Postmenopausal Women.

Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials.

Cyclooxygenase-2 polymorphisms, aspirin treatment, and risk for colorectal adenoma recurrence–data from a randomized clinical trial.

Aspirin is associated with lower melanoma risk among postmenopausal Caucasian women: the Women’s Health Initiative.

Case–Control Study of Aspirin Use and Risk of Pancreatic Cancer

Aspirin Use and Reduced Risk of Pancreatic Cancer.

Obesity, Aspirin, and Risk of Colorectal Cancer in Carriers of Hereditary Colorectal Cancer: A Prospective Investigation in the CAPP2 Study

Estimates of benefits and harms of prophylactic use of aspirin in the general population

Aspirin, lysine, mifepristone and doxycycline combined can effectively and safely prevent and treat cancer metastasis: prevent seeds from gemmating on soil

Is aspirin use associated with a decreased risk of ovarian cancer? A systematic review and meta-analysis of observational studies with dose-response analysis.

Regular and low-dose aspirin, other non-steroidal anti-inflammatory medications and prospective risk of HER2-defined breast cancer: the California Teachers Study

Aspirin-Mediated Acetylation Protects Against Multiple Neurodegenerative Pathologies by Impeding Protein Aggregation.

Aspirin: a review of its neurobiological properties and therapeutic potential for mental illness

Aspirin suppresses the abnormal lipid metabolism in liver cancer cells via disrupting an NFκB-ACSL1 signaling.

Salicylic acid attenuates virulence in endovascular infections by targeting global regulatory pathways in Staphylococcus aureus

Unlocking Aspirin’s Chemopreventive Activity: Role of Irreversibly Inhibiting Platelet Cyclooxygenase-1

Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials

Risk of prostate cancer in low-dose aspirin users: A retrospective cohort study.

Analgesic medication use and risk of epithelial ovarian cancer in African American women

Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer

A Switch from White to Brown Fat Increases Energy Expenditure in Cancer-Associated Cachexia

ARF and p53 coordinate tumor suppression of an oncogenic IFN-β-STAT1-ISG15 signaling axis

Aspirin and salicylates inhibit the IL-4- and IL-13-induced activation of STAT6.

Aspirin for the prevention of colorectal cancer

Aspirin therapy reduces the ability of platelets to promote colon and pancreatic cancer cell proliferation: implications for the oncoprotein c-MYC.

Analgesic use and sex steroid hormone concentrations in postmenopausal women

Aspirin is associated with lower melanoma risk among postmenopausal Caucasian women: the Women’s Health Initiative

Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity

2306 Aspirin and gastro intestinal malignancies; improved survival not only in colorectal cancer?

Aspirin Use and Colorectal Cancer Survival According to Tumor CD274 (Programmed Cell Death 1 Ligand 1) Expression Status

Aspirin in the Treatment of Cancer: Reductions in Metastatic Spread and in Mortality: A Systematic Review and Meta-Analyses of Published Studies

Use of Aspirin postdiagnosis improves survival for colon cancer patients

Effect of low-dose aspirin use on survival of patients with gastrointestinal malignancies; an observational study

Survival Benefits for Low-Dose Aspirin in GI Cancers

Long-Term Effects of Aspirin on Colorectal Cancer

NSAIDs Use and Reduced Metastasis in Cancer Patients: results from a meta-analysis

Aspirin, cyclooxygenase inhibition and colorectal cancer

Antitumor effect of aspirin in glioblastoma cells by modulation of β-catenin/T-cell factor-mediated transcriptional activity.

Salicylate Downregulates 11β-HSD1 Expression in Adipose Tissue in Obese Mice and in Humans, Mediating Insulin Sensitization

Induction of proto-oncogene BRF2 in breast cancer cells by the dietary soybean isoflavone daidzein

Cellular Fatty Acid Metabolism and Cancer

Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction

Cyclooxygenase-derived proangiogenic metabolites of epoxyeicosatrienoic acids.

Chronic cellular hypoxia as the prime cause of cancer: what is the de-oxygenating role of adulterated and improper ratios of polyunsaturated fatty acids when incorporated into cell membranes?

Prevention of fat-induced insulin resistance by salicylate

Evaluation of nootropic and neuroprotective effects of low dose aspirin in rats

Low-dose aspirin and cancer mortality: a meta-analysis of randomized trials.




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